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Boosting a Protein in Aging Mice Makes Them Stronger and Healthier

Published on June 22, 2026, 11:30 a.m.
Boosting a Protein in Aging Mice Makes Them Stronger and Healthier

Topic: Research News

Scientists found that boosting a protein called tristetraprolin (TTP) in aging mice made them stronger and healthier. This could help people stay healthy as they age.

As the US population ages, scientists are searching for ways to help people stay healthier later in life. By 2050, nearly one in four Americans will be age 65 or older, and many are expected to live well into their 90s. While modern medicine has dramatically extended lifespan, aging still brings serious physical challenges, including weaker immunity, chronic inflammation, bone loss, fatigue, and declining strength.

Researchers at the University at Buffalo believe they may have found an important clue for slowing some of those age-related changes. They focused on a constant, low-level state of inflammation that gradually damages tissues and weakens the body. This process is called

Implications

Scientists found that boosting a protein called tristetraprolin (TTP) in aging mice made them stronger and healthier. This could help people stay healthy as they age.


Source: https://www.sciencedaily.com/releases/2026/05/260518041436.htm

Journal Reference:

  1. Ramkumar Thiyagarajan, Lixia Zhang, Leticia Andrea Rojas Cortez, Kyu Hwan Kwack, Victoria Maglaras, Nanda Kumar Yellapu, Yukitomo Arao, Kenneth L. Seldeen, Perry J. Blackshear, Bruce R. Troen, Keith L. Kirkwood. Increased Stability of Tristetraprolin mRNA Supports Bone Health and Decreases Frailty During Aging. Aging and Disease, 13 January 2026 DOI: 10.14336/AD.2025.1243

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