Topic: Health
A new study found that a drug called solriamfetol helps people who work early morning shifts stay awake and alert. This is important because many people struggle with severe fatigue linked to shift work disorder.
This condition can make it hard for workers to concentrate, perform their job well, and even stay safe. A team of researchers at Mass General Brigham led a clinical trial to test the drug solriamfetol (Sunosi) on early morning shift workers. The study was published in NEJM Evidence.
The researchers found that people who took the drug were less sleepy and could stay awake longer during simulated work hours. They also reported better overall functioning, improved work performance, and greater ability to manage daily tasks.
The study included 78 early morning shift workers diagnosed with shift work disorder. Participants took either solriamfetol or a placebo on workdays over a four-week period. The researchers assessed their ability to stay awake in a controlled setting during hours that matched their typical work schedule.
The findings are promising because they show that the drug can help people who start their day when most people are still asleep. This is important for many workers who operate outside the standard 9-to-5 schedule.
Why It Matters
This study matters to Indian students because it shows that there are ways to help people who work non-traditional hours stay awake and alert. Many students in India may have family members or friends who work early morning shifts, and this research can help them understand the challenges these workers face.
Key Facts
- The study included 78 early morning shift workers diagnosed with shift work disorder.
- Participants took either solriamfetol or a placebo on workdays over a four-week period.
- The researchers found that people who took the drug were less sleepy and could stay awake longer during simulated work hours.
Key Terms
- Solriamfetol
- A wake-promoting drug that helps people stay awake and alert
Implications
This study matters to Indian students because it shows that there are ways to help people who work non-traditional hours stay awake and alert. Many students in India may have family members or friends who work early morning shifts, and this research can help them understand the challenges these workers face.
Source: https://www.sciencedaily.com/releases/2026/04/260401071936.htm
Journal Reference:
- Kirsi-Marja Zitting, Katherine R. Gilmore, Brandon J. Lockyer, Eileen B. Leary, Wei Wang, Nicolas C. Issa, Stuart F. Quan, Jonathan S. Williams, Jeanne F. Duffy, Charles A. Czeisler. Solriamfetol for Excessive Sleepiness in Early-Morning Shift Work Disorder. NEJM Evidence, 2026; 5 (2) DOI: 10.1056/EVIDoa2500190
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