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Rice Bran Compound May Help Ease Irritable Bowel Symptoms

Mayur Tembhare
  1. Ferulic acid is a compound found in rice bran that has antioxidant and neuroprotective effects.

  2. The researchers tested ferulic acid on guinea pig intestines and found that it reduced contractions triggered by certain signaling molecules.

  3. Ferulic acid acts by blocking voltage-dependent calcium channels, which are involved in muscle contraction.

  4. People with IBS and IBD often experience abnormal intestinal movement, which can cause symptoms like diarrhea or constipation.

Rice Bran Compound May Help Ease Irritable Bowel Symptoms

Topic: Health

A team of scientists from Toho University found that a compound in rice bran can reduce intestinal contractions. This could lead to new treatments for irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Scientists at Toho University have discovered that ferulic acid, a compound found in rice bran, can help ease symptoms of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Ferulic acid is a type of antioxidant that is already known for its health benefits. It's found in many plant-based foods, especially whole grains and rice bran.

The researchers tested ferulic acid on guinea pig intestines and found that it reduced contractions triggered by certain signaling molecules. They also discovered that ferulic acid acts by blocking voltage-dependent calcium channels, which are involved in muscle contraction.

This finding is important because people with IBS and IBD often experience abnormal intestinal movement. In some cases, the gut contracts too much, while in others, movement is reduced. The researchers hope that their discovery could lead to new dietary approaches for these conditions.

Why It Matters

Irritable bowel syndrome (IBS) affects millions of people worldwide, including many Indians. If ferulic acid can help ease symptoms, it could improve the quality of life for those suffering from this condition.

Key Facts

  • Ferulic acid is a compound found in rice bran that has antioxidant and neuroprotective effects.
  • The researchers tested ferulic acid on guinea pig intestines and found that it reduced contractions triggered by certain signaling molecules.
  • Ferulic acid acts by blocking voltage-dependent calcium channels, which are involved in muscle contraction.
  • People with IBS and IBD often experience abnormal intestinal movement, which can cause symptoms like diarrhea or constipation.
  • The researchers hope that their discovery could lead to new dietary approaches for IBS and IBD.

Key Terms

Ferulic acid
A type of antioxidant found in plant-based foods, including rice bran.
Voltage-dependent calcium channels
Channels that allow calcium ions to enter muscle cells, triggering contraction.

Implications

Irritable bowel syndrome (IBS) affects millions of people worldwide, including many Indians. If ferulic acid can help ease symptoms, it could improve the quality of life for those suffering from this condition.

Source: https://www.sciencedaily.com/releases/2026/07/260729010742.htm

Journal reference:

  1. Keisuke Obara, Kento Yoshioka, Aya Shimada, Sakika Ichihara, Wakaba Kinami, Futaba Makino, Naho Takazakura, Miwa Enomoto, Yoshio Tanaka. Ferulic acid suppresses guinea pig ileal longitudinal smooth muscle contractions by inhibiting voltage-dependent Ca2 channels. Journal of Pharmacological Sciences, 2025; 158 (4): 289 DOI: 10.1016/j.jphs.2025.05.012

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