Topic: Biology
Researchers found a new protein that helps sea anemones fight viruses. This discovery shows that animals have different ways to protect themselves from infections.
Scientists at the Hebrew University of Jerusalem and the University of North Carolina at Charlotte discovered a new way that sea anemones defend against viruses. They found a protein called CARDIB, which is similar to a protein in humans called MAVS. However, instead of helping to fight viruses like MAVS does, CARDIB actually slows down the immune system.
The researchers were surprised by this discovery and wanted to learn more about how it works. They used CRISPR gene editing to remove the CARDIB gene from sea anemones and then exposed them to viruses. The results showed that without CARDIB, the sea anemones became much more susceptible to infection. This means that CARDIB is actually essential for helping sea anemones fight off viruses.
The researchers also tested their findings in a natural environment by moving genetically modified sea anemones into outdoor marine mesocosms. They found that these animals accumulated more viruses than unmodified ones, confirming their discovery.
Why It Matters
This discovery is important because it shows that animals have different ways to protect themselves from infections. This can help us understand how to develop new treatments for diseases in humans and other animals.
Key Facts
- Scientists at the Hebrew University of Jerusalem and the University of North Carolina at Charlotte discovered a new protein called CARDIB that helps sea anemones fight viruses.
- CARDIB is similar to a protein in humans called MAVS, but it slows down the immune system instead of helping to fight viruses.
- The researchers used CRISPR gene editing to remove the CARDIB gene from sea anemones and found that they became more susceptible to infection without it.
- The discovery was confirmed by testing genetically modified sea anemones in a natural environment.
Key Terms
- CRISPR
- A tool used to edit genes, allowing scientists to make specific changes to an organism's DNA.
Implications
This discovery is important because it shows that animals have different ways to protect themselves from infections. This can help us understand how to develop new treatments for diseases in humans and other animals.
Source: https://www.sciencedaily.com/releases/2026/06/260630020534.htm
Journal Reference:
- Ton Sharoni, Adrian Jaimes-Becerra, Sydney Birch, Hee-Jin Kwak, Daria Aleshkina, Magda Lewandowska, Joachim M. Surm, Hannah Justin, Reuven Aharoni, Adam M. Reitzel, Yehu Moran. An ancient anthozoan protein reveals an alternative evolutionary path of antiviral signalling. Nature Ecology, 2026; DOI: 10.1038/s41559-026-03112-3
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