Topic: Neuroscience
A team of scientists has mapped every connection between neurons in a fruit fly's brain and body. This helps us understand how our brains and bodies work together to control movements.
Fruit flies are simple creatures, but they can still perform complex behaviors like navigating and interacting with each other. Scientists have been studying their nervous system to learn more about how it works. Recently, a team of researchers from Harvard Medical School and Princeton University published a complete map of every connection between neurons in the central nervous system of an adult fruit fly. This is called a connectome. It's like having a blueprint for the fruit fly's brain and body connections.
The new map includes the fruit fly's spinal cord equivalent, which controls its legs, wings, and other appendages. By studying this map, scientists can see how information moves between the brain and the body. They found that many fruit fly behaviors are directed by local neural circuits in specific parts of the body, rather than a central command area in the brain.
This breakthrough gives scientists a new way to examine how our brains and bodies work together to produce complex actions. It also opens the door to broader studies of the core rules that govern nervous systems.
Why It Matters
Understanding how our brains and bodies work together is crucial for developing treatments for neurological disorders. This research can also help us better understand animal behavior, which is important for conservation efforts.
Key Facts
- A team of scientists from Harvard Medical School and Princeton University mapped every connection between neurons in a fruit fly's brain and body.
- The new map includes the fruit fly's spinal cord equivalent, which controls its legs, wings, and other appendages.
- Many fruit fly behaviors are directed by local neural circuits in specific parts of the body, rather than a central command area in the brain.
Key Terms
- Connectome
- A complete map of every connection between neurons in an organism's brain and body
Implications
Understanding how our brains and bodies work together is crucial for developing treatments for neurological disorders. This research can also help us better understand animal behavior, which is important for conservation efforts.
Source: https://www.sciencedaily.com/releases/2026/06/260610003047.htm
Journal Reference:
- Alexander S. Bates, Jasper S. Phelps, Minsu Kim, Helen H. Yang, Arie Matsliah, Zaki Ajabi, Eric Perlman, Kevin M. Delgado, Mohammed Abdal Monium Osman, Christopher K. Salmon, Jay Gager, Benjamin Silverman, Sophia Renauld, Farzaan Salman, Janki Patel, Matthew F. Collie, Jingxuan Fan, Diego A. Pacheco, Yunzhi Zhao, Wenyi Zhang, Laia Serratosa Capdevila, Ruairí J. V. Roberts, Eva J. Munnelly, Nina Griggs, Helen Langley, Borja Moya-Llamas, Zuoyu Zhang, Ryan T. Maloney, Szi-chieh Yu, Amy R. Sterling, Marissa Sorek, Krzysztof Kruk, Nikitas Serafetinidis, Serene Dhawan, Finja Klemm, Paul Brooks, Ellen Lesser, Jessica M. Jones, Sara E. Pierce-Lundgren, Su-Yee Lee, Yichen Luo, Andrew P. Cook, Theresa H. McKim, Dimitrios Stasi Giakoumas, Benjamin Gorko, Justin Ellis-Joyce, Jiayi Zhang, Emily C. Kophs, Tjalda Falt, Alexa M. Negron-Morales, Austin Burke, James Hebditch, Kyle P. Willie, Ryan Willie, Sergiy Popovych, Nico Kemnitz, Dodam Ih, Kisuk Lee, Ran Lu, Akhilesh Halageri, J. Alexander Bae, Ben Jourdan, Gregory Schwartzman, Damian D. Demarest, Emily Behnke, Doug Bland, Anne Kristiansen, Jaime Skelton, Tom Stocks, Dustin Garner, Anthony Hernandez, Sandeep Kumar, Jasper S. Phelps, Minsu Kim, Farzaan Salman, Ryan T. Maloney, Dimitrios Stasi Giakoumas, Benjamin L. de Bivort, Anna Verbe, Gabriel A. Nieves-Sanabria, Devon Jones, Zijin Huang, Sofia Pinto, Celia David, Omaris Y. De Pablo-Crespo, Emily Ye, Wolf Huetteroth, Zequan Liu, Fernando J. Figueroa Santiago, Kevin C. Daly, Sven Dorkenwald, Forrest Collman, Marie P. Suver, Lisa M. Fenk, Michael J. Pankratz, Zepeng Yao, Fei Wang, Stephen J. Huston, Tomke Stürner, Gregory S. X. E. Jefferis, Katharina Eichler, Andrew M. Seeds, Stefanie Hampel, Sweta Agrawal, Tatsuo S. Okubo, Meet Zandawala, Thomas Macrina, Diane-Yayra Adjavon, Jan Funke, John C. Tuthill, Anthony Azevedo, H. Sebastian Seung, Benjamin L. de Bivort, Mala Murthy, Jan Drugowitsch, Rachel I. Wilson, Wei-Chung Allen Lee. Distributed control circuits across a brain-and-cord connectome. Nature, 2026; DOI: 10.1038/s41586-026-10735-w
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