Skip to main content
Admissions guidance, study banks, and career tools — get started on Shalyam
Research News

Shingles Vaccine May Help Prevent Dementia in Older Adults

Mayur Tembhare
  1. Over 500,000 older adults were analyzed in the study.

  2. The researchers found that vaccinated adults had a 24% lower risk of dementia compared to those who did not receive the vaccine.

  3. Shingrix is the only shingles vaccine available on the market and was introduced in 2017.

  4. The study's lead author, Kaley Hayes, said that this new vaccine is different from older ones, which may have contributed to its effectiveness in preventing dementia.

Shingles Vaccine May Help Prevent Dementia in Older Adults

Topic: Health

A new study found that older adults who received a shingles vaccine had a 24% lower risk of developing dementia. Researchers analyzed data from over 500,000 adults aged 66 and older who were admitted to skilled nursing facilities between 2017 and 2022.

Older adults who got the shingles vaccine after moving into a skilled nursing facility were less likely to be diagnosed with dementia over the next four years. This is according to a new study that looked at data from over 500,000 adults aged 66 and older who were admitted to these facilities between 2017 and 2022.

The researchers compared patients who received at least one dose of the shingles vaccine called Shingrix with those who did not get vaccinated. They found that vaccinated adults had a 24% lower risk of dementia compared to those who did not receive the vaccine.

Shingrix is the only shingles vaccine available on the market, and it was introduced in 2017. The study's lead author, Kaley Hayes, said that this new vaccine is different from older ones, which may have contributed to its effectiveness in preventing dementia.

The researchers used a technique called target trial emulation to analyze the data. This approach tries to recreate the conditions of a randomized clinical trial, which would be difficult to conduct with such a large number of participants.

One important limitation of the study is that it cannot prove whether the shingles vaccine directly reduces the risk of dementia. However, the findings suggest that an already widely accessible preventive measure could potentially benefit both physical and cognitive health.

Why It Matters

This study's findings are relevant to India because older adults in the country may also be at risk for dementia. If a simple vaccine can help prevent this condition, it could have significant implications for public health in India.

Key Facts

  • Over 500,000 older adults were analyzed in the study.
  • The researchers found that vaccinated adults had a 24% lower risk of dementia compared to those who did not receive the vaccine.
  • Shingrix is the only shingles vaccine available on the market and was introduced in 2017.
  • The study's lead author, Kaley Hayes, said that this new vaccine is different from older ones, which may have contributed to its effectiveness in preventing dementia.
  • The researchers used a technique called target trial emulation to analyze the data.

Key Terms

Shingrix
A shingles vaccine introduced in 2017 and currently the only one available on the market.
Target Trial Emulation
A technique used to analyze data by recreating the conditions of a randomized clinical trial.

Implications

This study's findings are relevant to India because older adults in the country may also be at risk for dementia. If a simple vaccine can help prevent this condition, it could have significant implications for public health in India.

Source: https://www.sciencedaily.com/releases/2026/08/260823015013.htm

Journal reference:

  1. Kaleen N. Hayes, Daniel A. Harris, Kevin W. McConeghy, Lexie R. Grove, Richa Joshi, Lisa Han, H. Edward Davidson, Preeti Chachlani, Thomas A. Bayer, Mriganka Singh, Yasin Abul, Frank DeVone, Stefan Gravenstein. Dementia Risk After Recombinant Herpes Zoster Vaccination in Older Adults With a Recent Skilled-Nursing Facility Stay. Annals of Internal Medicine, 2026; 179 (7): 958 DOI: 10.7326/ANNALS-25-04689

Leave a comment

← All research

Get Exclusive Insights with Every Issue

Join Shalyam Newsletter

Stay ahead in education, research, and innovation—straight to your inbox.