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Alzheimer's Research

Explore the latest discoveries and stories in Alzheimer's Research. Stay updated with research that shapes education, technology, and innovation.

Glycated amyloid-β sneaks into mitochondria, forces mtDNA leakage through VDAC1, and ignites cGAS-STING inflammation — a new molecular explanation for why diabetes accelerates Alzheimer’s
Alzheimer's Research

Glycated amyloid-β sneaks into mitochondria, forces mtDNA leakage through VDAC1, and ignites cGAS-STING inflammation — a new molecular explanation for why diabetes accelerates Alzheimer’s

A landmark PNAS paper (16 Nov 2025) finally explains why diabetes doubles Alzheimer’s risk: sugar-damaged (“glycated”) amyloid-β sneaks into neuronal mitochondria, forces the pore …

Nov 30, 2025 Mayur Tembhare
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In the race to solve Alzheimer's disease, scientists find more needles in the haystack
Alzheimer's Research

In the race to solve Alzheimer's disease, scientists find more needles in the haystack

The International Genomics of Alzheimer's Project (IGAP) analyzed millions of genetic variants to come up with the latest listing of 75 variations associated with …

Apr 21, 2022 Mayur Tembhare
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Unexpected protein could play role in common brain disorder
Alzheimer's Research

Unexpected protein could play role in common brain disorder

Scientists report that amyloid fibrils found in people with frontotemporal degeneration contain the little-known protein TMEM106B.

Apr 20, 2022 Mayur Tembhare
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Cross-racial study of 1.87m vets shows wide disparities in dementia
Alzheimer's Research

Cross-racial study of 1.87m vets shows wide disparities in dementia

In what is believed to be the largest study to date on race and dementia, researchers tracked health and demographic data from close to …

Apr 20, 2022 Mayur Tembhare
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Psychiatric symptoms in Alzheimer´s disease
Alzheimer's Research

Psychiatric symptoms in Alzheimer´s disease

In addition to memory problems and other cognitive symptoms, most people with Alzheimer's disease also suffer from mental health issues. It has long been …

Apr 19, 2022 Mayur Tembhare
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Key signaling pathway in immune cells could be new Alzheimer’s target
Alzheimer's Research

Key signaling pathway in immune cells could be new Alzheimer’s target

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other …

Apr 15, 2022 Mayur Tembhare
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Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia
Alzheimer's Research

Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia

Frontotemporal dementia patients with extrapyramidal symptoms have brainstem atrophy and reduced metabolism in certain areas of the brain significantly more often than patients without …

Apr 8, 2022 Mayur Tembhare
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Alzheimer‘s: Amyloid and tau are a perilous couple
Alzheimer's Research

Alzheimer‘s: Amyloid and tau are a perilous couple

In the course of Alzheimer's disease, two proteins called 'amyloid' and 'tau' accumulate in the brain. A new study with more than 200 participants …

Mar 30, 2022 Mayur Tembhare
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Promising Alzheimer's drug may also improve memory in Down syndrome and normal aging
Alzheimer's Research

Promising Alzheimer's drug may also improve memory in Down syndrome and normal aging

New research is breaking ground in repurposing an FDA-approved drug as a potential treatment in Down syndrome and normal aging. The results suggest that …

Mar 30, 2022 Mayur Tembhare
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New information about amyloid filaments in neurodegenerative diseases
Alzheimer's Research

New information about amyloid filaments in neurodegenerative diseases

Researchers have helped identify that a common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner without a connection to disease.

Mar 29, 2022 Mayur Tembhare
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Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model
Alzheimer's Research

Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model

Researchers found that niacin limits Alzheimer's disease progression when used in models in the lab, a discovery that could potentially pave the way toward …

Mar 24, 2022 Mayur Tembhare
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Neuroscientists identify mechanism for long term memory storage
Alzheimer's Research

Neuroscientists identify mechanism for long term memory storage

While studying how memories are formed and stored in the brain, a team identified a novel protein folding mechanism that is essential for long …

Mar 24, 2022 Mayur Tembhare
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